Popis: |
Management of young patients with breast cancer still poses challenge to clinicians. Higher occurrence of aggressive intrinsic breast cancer subtypes and clinically advanced disease at diagnosis are observed in this patient population. Yet, they do not provide a full explanation for the poor clinical outcome observed in younger patients. Increasingly, the role tumor biology, irrespective of the underlying intrinsic breast cancer subtype, is being recognized as a predictor of worse outcome in young breast cancer patients. |