Factors associated with the lethality of patients hospitalized with severe acute respiratory syndrome due to COVID-19 in Brazil

Autor: Brunnella Alcantara Chagas de Freitas, Ana Cristina Dias Custódio, Cristiane Junqueira de Carvalho, Fábio Vieira Ribas, Luciana Lima, Luana Vieira Toledo
Rok vydání: 2022
Zdroj: PLOS Global Public Health. 2:e0000200
ISSN: 2767-3375
Popis: Due to the high rates of transmission and deaths due to COVID-19, understanding the factors associated with its occurrence, as well as monitoring and implementing control measures should be priority actions in health surveillance, highlighting the use of epidemiological surveillance information systems as an important ally. Thus, the objectives of this study were to calculate the mortality rate of hospitalized patients with severe acute respiratory syndrome due to COVID-19 and to identify factors associated with death, in the period corresponding to epidemiological weeks 01 to 53 of the year 2020. This was a longitudinal study, using the national influenza epidemiological surveillance information system database, routinely collected by healthcare services. The sociodemographic and clinical characteristics of 563,051 hospitalized patients with severe acute respiratory syndrome due to COVID-19 in the five regions of Brazil were analyzed. Cox regression was performed to assess factors associated with patient death during hospitalization. The national lethality rate was 35.7%, and the highest rates of lethality occurred in the Northeast (44.3%) and North (41.2%) regions. During the hospital stay, death was associated with older age (Hazard Ratio—HR = 1.026; p
Databáze: OpenAIRE