Autor:	T. Lowdon, P. G. Wainwright, Barry Lygo, John Crosby
Rok vydání:	1999
Předmět:	Sharpless epoxidation chemistry.chemical_compound Chemistry Stereochemistry Dihydroxylation Organic Chemistry Drug Discovery Ring (chemistry) Biochemistry Quinuclidine
Zdroj:	Tetrahedron. 55:2795-2810
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(99)00050-2
Popis:	Highly enantio- and diastereoselective routes to 2-hydroxymethylquinuclidines have been developed. Key steps involve the use of Sharpless dihydroxylation or Sharpless epoxidation to introduce the asymmetry with high stereocontrol, and formation of the quinuclidine ring systems via cyclisation of epoxy amines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5ded851fda68e28290e99755f7eef3bb https://doi.org/10.1016/s0040-4020(99)00050-2 Zobrazit plný text záznamu Full Text from ScienceDirect