Infective endocarditis
| Autor: | George E. Reed, Frank C. Spencer, Anthony J. Acinapura, Isom Ow, David A. Tice, Arthur D. Boyd, Joseph N. Cunningham |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty business.industry medicine.medical_treatment Mortality rate medicine.disease Surgery Sepsis Valve replacement Infective endocarditis medicine University medical Embolization Cardiology and Cardiovascular Medicine business Surgical treatment Medical therapy |
| Zdroj: | The Journal of Thoracic and Cardiovascular Surgery. 73:23-30 |
| ISSN: | 0022-5223 |
| DOI: | 10.1016/s0022-5223(19)39978-7 |
| Popis: | One hundred seventy-seven patients were admitted to the New York University Medical Center from 1970 through 1975 with infective endocarditis. Fifty-four of these patients required surgical treatment. The over-all mortality rate was 28 per cent. Two thirds of the deaths were early (10 patients) and one third late (5 patients). The mortality rate was 90 per cent in 10 patients treated for 4 to 6 weeks in whom the infection was uncontrolled and the clinical condition was deteriorating. However, of the 12 patients with uncontrolled infection who were operated upon promptly within 10 days, 83 per cent survived. The fact that fungal and gram-negative infections responded poorly to medical therapy suggests the need for prompt, early surgical intervention. The mortality rate in the 32 patients operated upon in whom the infection was controlled was 12.5 per cent. It is our conclusion that all patients with infective endocarditis who develop progressive congestive failure, recurrent embolization, or progressive sepsis, despite treatment, should have prompt valve replacement within 7 days of the institution of appropriate antimicrobial therapy. |
| Databáze: | OpenAIRE |
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