| Popis: |
Summary The Peking White duckling is suitable for the bioassay of aflatoxin. Aflatoxin causes liver damage in the birds 1–2 days after oral administration. The LD 50 of our aflatoxin sample A16A was 1.40 mg/kg. The lower limit of liver damage detection after a single dose is 0.1 mg/kg; it can be reduced by a factor of 10 with multiple dosage. The multiple dosage protocol is suitable for qualitative screening, but an LD 50 determination is recommended for quantitative measurements. We recommend that mycological, chemical, and toxicologic results be considered in a qualitative interpretation of aflatoxin poisoning. |
