Expression of Stearoyl Co-enzyme A desaturase (SCD) gene during the juvenile age in layer chicken
| Autor: | A. Rajendra Prasad, Rajshekhar Chatterjee, N. Govardhana Sagar, K. K. Kanaka, Pushpendra Kumar, T. K. Bhattacharya, Bharat Bhushan |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Messenger RNA General Veterinary Cholesterol Mrna expression Biology chemistry.chemical_compound Endocrinology Enzyme Expression pattern chemistry hemic and lymphatic diseases Internal medicine medicine Juvenile Animal Science and Zoology Serum triglycerides Gene |
| Zdroj: | Indian Journal of Animal Research. |
| ISSN: | 0976-0555 0367-6722 |
| DOI: | 10.18805/ijar.b-3698 |
| Popis: | Stearoyl-CoA desaturase (SCD) is key enzyme in the production of triglycerides and cholesterol. Present study was conducted to know the expression pattern of the Stearoyl-CoA desaturase (SCD) gene in liver during juvenile age (0 day, 14th day, 28th day and 42nd day) in layer birds. Expression of SCD gene increased from the day of hatch to 42nd day, as the body weight and fat deposition increased. The mRNA expression levels of SCD gene during day 0 was differed significantly (P less than 0.05) with expression levels during other juvenile ages. When compared with SCD expression levels on the day 0 expression levels were up-regulated by 8198.64, 7245.99 and 5587.77 folds over day 14, 28 and 42 respectively. Serum concentration of triglycerides and cholesterol were found to be proportional to the expression levels of SCD gene in liver. It is concluded that SCD expression varied among different age groups during juvenile stages and had significant association with serum triglycerides and cholesterol concentration in layer chicken. |
| Databáze: | OpenAIRE |
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