Substitution électrophile aromatique. IV. Effets stériques dans la réaction d'iodo-démétallation de dérivés organostanniques aromatiques

Autor:	Richard Martin, B. Wilmet‐Devos, Mireille Grosjean, Ouri Buchman, Jacques Nasielski
Rok vydání:	1964
Předmět:	Steric effects Silicon Chemistry Stereochemistry Organic Chemistry Leaving group chemistry.chemical_element Hydrogen atom Iodine Biochemistry Medicinal chemistry Catalysis Inorganic Chemistry Germanium compounds Drug Discovery Reactivity (chemistry) Physical and Theoretical Chemistry Ground state
Zdroj:	Helvetica Chimica Acta. 47:1688-1695
ISSN:	0018-019X
DOI:	10.1002/hlca.19640470704
Popis:	Aromatic organo‐tin compounds ArSnR3 have been synthesized with R = n‐butyl and R = i‐propyl. Increased bulk of the leaving group results in lower reactivity towards iodine, showing appreciable interactions between the incoming and leaving groups. A peri hydrogen atom induces a secondary steric acceleration, suggesting that the ground state for large R3Sn substituents in 1‐naphthyl systems is strained. This agrees with previous reports by EABORN et coll. [14] relating to the corresponding silicon and germanium compounds. Copyright © 1964 Verlag GmbH & Co. KGaA, Weinheim
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5dc81c0a9d8cea55fdeb9c4bae1213e6 https://doi.org/10.1002/hlca.19640470704 Zobrazit plný text záznamu Plný text