Application of fast atom bombardment mass spectrometry for the analysis of biologically active compounds

Autor:	K. J. van der Merwe, Pieter Swart, L. Fourie, S. S. de Kock
Rok vydání:	1993
Předmět:	Analytical chemistry Biological activity Aziridine Fast atom bombardment Mass spectrometry Biochemistry Mass spectrometric Combinatorial chemistry Analytical Chemistry Matrix (chemical analysis) chemistry.chemical_compound chemistry Environmental Chemistry Molecule Derivatization Spectroscopy
Zdroj:	Analytica Chimica Acta. 279:163-166
ISSN:	0003-2670
DOI:	10.1016/0003-2670(93)85079-y
Popis:	A fast atom bombardment (FAB) mass spectrometric method for structural studies on phenolic aziridines and their open-chain precursors is described. It was found that the presence of free phenolic groups put limitations on the FAB ionisation method previously described for the study of acetylated aziridines. A new method for structure confirmation of phenolic aziridines and their precursors is described in which thioglycerol is used for an situ derivatization as well as a FAB matrix.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5dc5f918530f0c2a9f9d7c7fa9a6d2d4 https://doi.org/10.1016/0003-2670(93)85079-y Zobrazit plný text záznamu