Palladium(II) catalyzed allylic rearrangement: Stereoselective synthesis of 2-substituted (e)-β acetoxy (or benzoyloxy)ethylidenecyclohexanes

Autor:	Yoshinao Tamaru, Eiji Nakajo, Yuuya Yamada, Z. Yoshida, Hirofumi Ochiai
Rok vydání:	1984
Předmět:	Reaction mechanism Allylic rearrangement Stereochemistry Organic Chemistry Diastereomer chemistry.chemical_element Biochemistry Catalysis chemistry.chemical_compound chemistry Drug Discovery Reactivity (chemistry) Stereoselectivity Acetonitrile Palladium
Zdroj:	Tetrahedron. 40:1791-1793
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(01)91131-7
Popis:	Diastereomeric mixtures of 2-substituted 1-vinyclyclohexyl acetates (or benzoates) are rearranged stereoselectively to 2-substituted (E)-β-acetoxy(or benzoyloxy)ethylidenecyclohexanes by the catalysis of bis(acetonitrile)palladium(II) chloride. A mechanism related to the stereoselectivity and reactivity is discussed in terms of the conformational requirements in a transition state.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5dc574f9faee2eff61f4f210e6f16a32 https://doi.org/10.1016/s0040-4020(01)91131-7 Zobrazit plný text záznamu