Evaluation of an iron-filtered epithermal neutron beam for neutron-capture therapy
| Autor: | P. H. McGinley, S. V. Musolino, Paul Kliauga, Ralph G. Fairchild, R. C. Greenwood |
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| Rok vydání: | 1991 |
| Předmět: |
Physics
business.industry Astrophysics::High Energy Astrophysical Phenomena Physics::Medical Physics Radiochemistry Neutron stimulated emission computed tomography General Medicine Neutron spectroscopy Neutron capture Absorbed dose Dosimetry Neutron Gamma spectroscopy Nuclear medicine business Beam (structure) |
| Zdroj: | Medical Physics. 18:806-816 |
| ISSN: | 0094-2405 |
| DOI: | 10.1118/1.596635 |
| Popis: | An epithermal neutron filter using iron, aluminum, and sulfur was evaluated to determine if the therapeutic performance could be improved with respect to aluminum--sulfur-based filters. An empirically optimized filter was developed that delivered a 93% pure beam of 24-keV epithermal neutrons. It was expected that a thick filter using iron with a density thickness {gt}200 g/cm{sup 2} would eliminate the excess gamma contamination found in Al--S filters. This research showed that prompt gamma production from neutron interactions in iron was the dominant dose component. Dosimetric parameters of the beam were determined from the measurement of absorbed dose in air, thermal neutron flux in a head phantom, neutron and gamma spectroscopy, and microdosimetry. |
| Databáze: | OpenAIRE |
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