Translocation (X;1) Associated with a Nonpapillary Carcinoma in a Young Woman
| Autor: | Alain Houlgatte, Christine Fouet, Michel Arborio, François Desangles, Philippe Camparo |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities Cancer Research medicine.medical_specialty Pathology Clinical marker Karyotype Chromosomal translocation Biology medicine.disease Endocrinology Renal cell carcinoma Internal medicine Genetics medicine Carcinoma Abnormality Young adult Molecular Biology |
| Zdroj: | Cancer Genetics and Cytogenetics. 113:141-144 |
| ISSN: | 0165-4608 |
| DOI: | 10.1016/s0165-4608(98)00261-1 |
| Popis: | We report a translocation (X;1)(p11.2;q21) associated with a nontubulopapillary renal cell carcinoma in a 23-year-old woman. To our knowledge this the first report of such an association. A review of the previously published cases of renal cell carcinoma with t(X;1) and its cytogenetic variants with Xp11.2 anomalies is included. The role of this karyotype abnormality as a clinical marker is discussed. The Xp11.2 abnormality could be a primary abnormality characterizing a particular type of RCC appearing in children and young adults of both sexes and in which the histological aspect is not specific. |
| Databáze: | OpenAIRE |
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