| Popis: |
Introduction: Schwannomatosis is a rare type of neurofibromatosis, usually affects people between ages 25 and 30 years old. Schwannomatosis causes tumors to develop on the cranial, spinal, and peripheral nerves. The most common symptoms are: chronic pain, which can occur anywhere in the body and can be disabling, numbness or weakness in various parts of the body, and muscle paresis. Two genes are known to cause schwannomatosis. Mutations of the genes SMARCB1 and LZTR1, which suppress tumors, are associated with this type of neurofibromatosis. We report the case of a patient victimized by schwannomas in the pelvic region and, as a consequence, neuromuscular injuries. Case Report: Patient under investigation of lesions in the lumbosacral plexus and clinical picture marked by pain in the iliopsoas muscle in the left pelvic region and ipsilateral involvement of the obturator nerve (mild paresis in the adduction of the thigh and allodynia in the anterolateral region). A positron emission tomography-computed tomography (PET-CT) study was carried out to assess the nodular findings. Elongated and nodular lesions were observed, with attenuation of soft tissues, located laterally to the left iliopsoas muscle. In the biopsy of one of the nodules, the result was compatible with schwannomas. Immunohistochemical assay confirmed the schwannomas to be positive for Sox10. Conclusion: The patient, in this case, will be surgically approached due to the topography of the lesion, which currently causes refractory pain and impaired mobility. |
