Protamine is an antagonist of Apelin receptor, and its activity is reversed by heparin

Autor: Barak, L.S., Le Gonidec, S., Wanecq, E., Roth, B.L., Masri, B., Audigier, Y., Huang, X.-P., Knibiehler, B., Bai, Y., Chaves-Almagro, C., Prats, H., Smith, A., Caron, M.G., Kang, H.J., Valet, P.
Jazyk: angličtina
Předmět:
Popis: In the accompanying Comment, Suzuki et al. confirmed our previous findings that the ketamine metabolite (2R,6R)-hydroxynorketamine (HNK) does not functionally inhibit the NMDAR at concentrations relevant to its antidepressant actions recently reported in mice (that is, approximately 10 μM).
Databáze: OpenAIRE