Synthesis, Characterization and Bioactivity of Three Carboxylic Arylhydrazone Compounds

Autor:	Wangting Wu Wangting Wu, Fengying Chen Fengying Chen, Fei Yuan, Fei Yuan Chengfang Qiao, Shuiyang He Shuiyang He, Chengfang Qiao, Zhenguo Jin
Rok vydání:	2020
Předmět:	Chemistry food and beverages General Chemistry Combinatorial chemistry Characterization (materials science)
Zdroj:	Journal of the chemical society of pakistan. 42:149-149
ISSN:	0253-5106
Popis:	Three novel carboxylic arylhydrazone compounds named 2- oxo propionic acid terephthalal acyl dihydrazone (1), 2-ketoglutaric acid terephthalal acyl dihydrazone (2) and 2-ketoglutaric acid salicyl- hydrazone (3) were prepared and characterized by elemental analysis, IR and 1H NMR. The antibacterial activities of 1 and 2 against wheat rust and coliform were investigated. The results showed that 1 had more excellent antibacterial properties than 2 against both wheat rust and coliform. In addition, the title compounds interaction with calf-thymus DNA (CT-DNA) were measured by fluorescence spectra method which indicating that they combined with CT-DNA by groove binding through hydrogen bonds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5d995b3642a03fd6611e7441c9cb5251 https://doi.org/10.52568/000611 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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