Mapping Physical Tumor Microenvironment and Drug Delivery
| Autor: | Hadi Tavakoli Nia, Rakesh K. Jain, Lance L. Munn |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Oncology Cancer Research medicine.medical_specialty Tumor microenvironment business.industry 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Internal medicine Drug delivery Tissue elasticity medicine Treatment strategy Biomarker (medicine) business |
| Zdroj: | Clinical Cancer Research. 25:2024-2026 |
| ISSN: | 1557-3265 1078-0432 |
| Popis: | The physical microenvironment of pancreatic tumors is highly abnormal, and this causes significant challenges for drug delivery through multiple mechanisms. Measurements of tissue elasticity could be used as a physical biomarker to assess aberrant drug delivery, and potentially guide stroma-targeting treatment strategies and patient stratification. See related article by Wang et al., p. 2136 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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