Highly Diastereoselective Synthesis of Cyclopentenones via a One-Pot Gold Catalysis, Nazarov Cyclization and Alkylation Cascade

Autor:	Jia-Qi Wang, Meng-Qi Liu, Ai-Hua Zhou, Long-Wu Ye, Shuang Jiang
Rok vydání:	2014
Předmět:	Cyclopentenone Chemistry education Organic Chemistry Alkylation Combinatorial chemistry humanities Catalysis Cycloaddition chemistry.chemical_compound Carboxylation Cascade reaction Organic chemistry Lewis acids and bases Trifluoromethanesulfonate
Zdroj:	Synthesis. 46:2161-2167
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-0033-1341204
Popis:	Starting from readily available propargylic carboxylates, three sequential transformations [gold-catalyzed tandem reaction, scandium(III) trifluoromethanesulfonate catalyzed Nazarov cyclization, alkylation reaction] in a one-pot process led to the formation of cyclopentenone derivatives in excellent diastereoselectivities and moderate to good overall yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5d8a48ca7498d7c6978995fbea622b1e https://doi.org/10.1055/s-0033-1341204 Zobrazit plný text záznamu