Effect of Echinacea purpurea tincture on the rat kidney antioxidant system under carbon tetrachloride intoxication

Autor:	I. F. Meshchyshen, N. F. Grigor’eva, I. V. Matsiopa
Rok vydání:	2012
Předmět:	Pharmacology Kidney Antioxidant biology Stereochemistry medicine.medical_treatment Rat kidney Tincture Glutathione Echinacea chemistry.chemical_compound medicine.anatomical_structure chemistry Catalase Drug Discovery Carbon tetrachloride medicine biology.protein
Zdroj:	Pharmaceutical Chemistry Journal. 46:441-442
ISSN:	1573-9031 0091-150X
DOI:	10.1007/s11094-012-0817-x
Popis:	The influence of Echinacea purpurea tincture on the state of rat kidney antioxidant system under carbon tetrachloride intoxication was studied. It was established that the content of TBA reaction products increased, the activity of catalase and glutathione transferase decreased, and the reduced glutathione level and the glutathione peroxidase activity increased in kidney supernatants from rats intoxicated with carbon tetrachloride. Administration of E. purpurea tincture for 5 d after carbon tetrachloride intoxication restored the glutathione peroxidase activity and corrected other antioxidant system parameters in rat kidneys.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5d8445ed637d22f8c581647190070c3a https://doi.org/10.1007/s11094-012-0817-x Zobrazit plný text záznamu Plný text ve formátu PDF