Bronchial Necrosis Following Bevacizumab and Stereotactic Body Radiotherapy for Treatment of Metastatic Breast Cancer
| Autor: | Umar Osman, Christopher R. Gilbert |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Bronchus Pathology Bevacizumab medicine.diagnostic_test business.industry medicine.medical_treatment respiratory system medicine.disease Metastatic breast cancer respiratory tract diseases Radiation therapy medicine.anatomical_structure Bronchoscopy Concomitant Medicine Radiology business Airway Adverse effect medicine.drug |
| Zdroj: | Journal of Pulmonary & Respiratory Medicine. 6 |
| ISSN: | 2161-105X |
| DOI: | 10.4172/2161-105x.1000345 |
| Popis: | Bevacizumab is an emerging therapy with widespread use in the treatment of advanced malignancies. We describe a young female with metastatic breast cancer that underwent stereotactic body radiation during treatment with bevacizumab after the discovery of a new metastatic focus within the lung parenchyma. Approximately one year later she presented with a progressive foul smelling cough and dyspnea. Bronchoscopy revealed extensive necrotic destruction of the bronchus intermedius. Airway necrosis may be a rare adverse event associated with the use of bevacizumab, especially with concomitant radiotherapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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