A novel ion selective PVC membrane electrode for determination of propranolol in pharmaceutical formulation

Autor:	Xian Xiang Sun, H.Y. Aboul-Enein
Rok vydání:	2000
Předmět:	Detection limit chemistry.chemical_compound Chromatography Membrane chemistry Electrode General Engineering Electroanalytical method General Chemistry Silicotungstic acid Pharmaceutical formulation Dosage form Ion selective electrode
Zdroj:	Analusis. 28:855-858
ISSN:	1286-482X 0365-4877
DOI:	10.1051/analusis:2000156
Popis:	A novel ion selective PVC membrane electrode for determination of propranolol is developed. Silicotungstic acid is used as the counter ion and diisononyl phthalate (DNP) used as the plastizer. The electrode exhibits excellent potential respon se properties, showing a Nernstian response in the concentration of 3.0 〈 10-6~ 2.6 〈 10-2 M with the slope of 54.7 mV per decade, shorter conditioning time (~ 3 h), fast response time (40 s), a lower limit of detection (1.0 〈 10-7 M). The electrode is success- fully used for the analysis of propranolol in pharmaceutical formulation with the recoveries of 99.2 ~ 102.6 %, by using a direct potentiometric method and which does not require tedious sample preparation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5d6cbbe56b360b331c832ea1d60e6272 https://doi.org/10.1051/analusis:2000156 Zobrazit plný text záznamu