Effects of Induced Haemorrahge on Thermoregulation, Blood Constituents and Serum Biochemical Parameters in Pregnant and Non-Pregnant Rabbits (Oryctolagus cuniculus)

Autor: Ahmed Omer Alameen, Khalid Abbas Owish Sukar, Abdalla M. Abdelatif
Rok vydání: 2019
Předmět:
Zdroj: Journal of Applied Life Sciences International. :1-15
ISSN: 2394-1103
DOI: 10.9734/jalsi/2019/v20i130072
Popis: Background and Objectives: Haemorrhage is a leading cause of mortality and morbidity of mother and foetus. Pregnancy is associated with changes which may influence responses to bleeding. This study was designed to examine the influence of controlled haemorrhage and compare thermoregulation and haematological and biochemical parameters in pregnant and nonpregnant rabbits. Materials and Methods: Twelve pregnant and nonpregnant rabbits, 6 in each group, were used in the studies. Both groups of animals were subjected to 20% haemorrhage of total blood volume on gestation day 21. The rectal temperature (Tr), respiratory rate (RR) and heart rate (HR) were monitored for 2 days following bleeding. Blood samples were collected at 24 hrs before induction of bleeding and then after bleeding at 30 min, 24 hrs and 48 hrs. The samples were used for measurements of haematological parameters; coagulation profile, arterial blood gases and serum electrolytes. Results: The general trend indicates lower Tr values in pregnant rabbits at 30 min post-haemorrhage. The values of RR and HR were significantly (P ≤ 0.01) higher in pregnant and nonpregnant animals at 24 hrs post-haemorrhage. The pregnant rabbits showed significant (P
Databáze: OpenAIRE