Effect of nitrogen on the antibacterial behavior of oxynitride glasses
| Autor: | Thomas J. Webster, Seniz R. Kushan Akin, Emrah Dölekçekiç |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
010302 applied physics
Materials science Process Chemistry and Technology Cationic polymerization chemistry.chemical_element 02 engineering and technology 021001 nanoscience & nanotechnology medicine.disease_cause 01 natural sciences Nitrogen Surfaces Coatings and Films Electronic Optical and Magnetic Materials Isoelectric point Chemical engineering chemistry 0103 physical sciences Materials Chemistry Ceramics and Composites medicine Amine gas treating Composition (visual arts) Wetting 0210 nano-technology Glass transition Escherichia coli |
| Zdroj: | Ceramics International. 47:18213-18217 |
| ISSN: | 0272-8842 |
| Popis: | The main drawback of bioglasses is their restricted use in load bearing applications and the consequent need to develop stronger glassy materials. This has led to the consideration of oxynitride glasses for numerous biomedical applications. This paper investigated two different types of glasses at a constant cationic ratio, with and without nitrogen (a N containing and a N-free glass composition) to better understand the effect of N on the biological properties of glasses. The results revealed that the addition of N increased the glass transition temperature, isoelectric point (IEP) and slightly increased wettability. Moreover, compared to N including glass, N-free glass exhibited better anti-bacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), two key bacteria that infect implants. In summary, these in vitro results indicated that amine functional groups existing in N containing glasses which are missing in N-free glasses, caused a slight difference in wetting behavior and a more obvious change in isoelectric point and in bacterial response. N-free glasses exhibited better inhibitory results both against E. coli and S. aureus compared to N including glass suggesting that oxygen rich glasses should be further studied for their novel antibacterial properties. |
| Databáze: | OpenAIRE |
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