Evaluation of delta-aminolevulinic acid levels in the urine of Angooran Lead & Zinc Company staff

Autor:	Heydarpour Fereidoun, Kalantari Soltanieh Sina, Heydarpour Pouria, Saadati Karim, Kalantari Soltanieh Sadraddin
Rok vydání:	2010
Předmět:	Chemistry Health Toxicology and Mutagenesis Urinary system Metallurgy Lead zinc Environmental Chemistry Physiology Delta Aminolevulinic Acid Urine Pollution Subclinical infection
Zdroj:	Toxicological & Environmental Chemistry. 92:1017-1023
ISSN:	1029-0486 0277-2248
DOI:	10.1080/02772240903126567
Popis:	Currently, attention has shifted to chronic or subclinical disorders attributed to lead (Pb) exposure. The aim of this study was to determine delta-aminolevulinic acid (δ-ALA) levels in urine of Angooran Lead & Zinc Company workers. This cross-sectional study was conducted on 170 workers, in which 24 h urinary samples were collected and δ-ALA levels were measured spectrophotometrically. Questionnaire forms were completed indicating age, location, and duration of work. The mean δ-ALA level in urine was 5.44 mg L−1. δ-ALA levels were correlated with age, location, and duration of work in the company. The mean δ-ALA level in the urine of workers was in the upper limit of normal ranges. δ-ALA level in urine may not be the best discriminating factor of Pb exposure from the baseline to the high levels, but is recommended as a regular and routine test for all Pb-exposed workers in addition to the measurement of Pb in blood for subjects with higher δ-ALA levels.
Databáze:	OpenAIRE
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