Pain unresponsive to high dose opiate drugs
| Autor: | Robert J Dickson, Psb Russell |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
medicine.medical_specialty
Chemotherapy business.industry medicine.medical_treatment General Medicine Malignant disease Surgery 03 medical and health sciences 0302 clinical medicine Anesthesiology and Pain Medicine Pharmacotherapy Nociception High dosage 030502 gerontology 030220 oncology & carcinogenesis Anesthesia Morphine Medicine Intractable pain Opiate 0305 other medical science business medicine.drug |
| Zdroj: | Palliative Medicine. 3:61-64 |
| ISSN: | 1477-030X 0269-2163 |
| DOI: | 10.1177/026921638900300110 |
| Popis: | Rarely the pain from malignant disease, primary or metastatic, cannot be adequately relieved by conventional analgesics, even with very high dosage opiate drugs. It is now recognized that in many instances this pain, of deafferentation type, is due to actual nerve infiltration or destruction by tumour. Five such cases are reported, in each of whom, a different manipulation of drug therapy was necessary before adequate pain control was achieved. It is concluded that, until a better understanding of the mechanism of deafferentation pain is reached, treatment of such cases will remain unsatisfactory. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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