ChemInform Abstract: Isolation and Characterization of an Unusual Nucleoside, 1-α-D- Ribofuranosyl-4-pyridone-3-carboxamide, from the Urines of Normal Human Individuals and Leukemic Patients

Autor:	Girish B. Chheda, S. P. Dutta, H. A. Tworek, Helen B. Patrzyc
Rok vydání:	2010
Předmět:	chemistry.chemical_compound chemistry medicine.drug_class Stereochemistry medicine Nucleic acid Carboxamide General Medicine Urine Spectral data Modified nucleosides 4-Pyridone Nucleoside
Zdroj:	ChemInform. 26
ISSN:	0931-7597
DOI:	10.1002/chin.199551267
Popis:	A novel modified nucleoside, 1-α-D-Ribofuranosyl-4-pyridone-3-carboxamide, has been isolated from the urines of one normal human individual and two CML patients. The structure was assigned on the basis of UV, NMR and mass spectral data and confirmed by comparison with an authentic sample synthesized in our laboratory. This constitutes the first example of the occurrence of a nucleoside with an α-riboside linkage in human urine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5d217ef4d20dc92556e2aca916f52e78 https://doi.org/10.1002/chin.199551267 Zobrazit plný text záznamu Plný text