Ion-exchange phenomena and concomitant pH shifts on the equilibration of reversed-phase packings with ion-pairing reagents

Autor:	R.H.A. Sorel, Jan Teeuwsen, A. W. M. Indemans, A. Hulshoff, O.A.G.J. van der Houwen
Rok vydání:	1981
Předmět:	Chromatography Ion exchange Chemistry Reagent Phase (matter) Ion pairing Organic Chemistry virus diseases General Medicine Biochemistry Analytical Chemistry Ion
Zdroj:	Journal of Chromatography A. 209:393-404
ISSN:	0021-9673
DOI:	10.1016/s0021-9673(00)80607-x
Popis:	Breakthrough patterns of eluents containing tetrabutylammonium or cetyltrimethylammonium ions (two frequently used ion-pairing agents in high-performance liquid chromatography) have been studied, using reversed-phase columns with octadecyl chains permanently bonded to 10-μm silica particles. The occurrence of pH shifts either before or after the breakthrough of the ion-pairing agents has been demonstrated. An explanation for the breakthrough patterns is offered and evidence for two different binding mechanisms of these agents is presented.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5d10889a69b2545a04d549e3778d09fd https://doi.org/10.1016/s0021-9673(00)80607-x Zobrazit plný text záznamu