ChemInform Abstract: Chemoenzymatic Synthesis of trans-4,5-Dihydroxycyclopent-2-enones: Conversion to D-1-Deoxynojirimycin
Autor: | Adam Golebiowski, Carl R. Johnson, John L. Esker, Bipin M. Nerurkar, Hari Sundram |
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Rok vydání: | 2010 |
Předmět: | |
Zdroj: | ChemInform. 26 |
ISSN: | 0931-7597 |
DOI: | 10.1002/chin.199541119 |
Popis: | (4R,5S)-trans-4,5-Bis(tert-butyldimethylsilyloxy)cyclopent-2-enone 8 and (4R,5S)-trans-4,5-di(benzyloxy)cyclopent-2-enone 20 are prepared by equilibration of the corresponding cis derivatives; enone 8 is transformed into the glucosidase inhibitor, D-1-deoxynojirimycin 14. |
Databáze: | OpenAIRE |
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