ChemInform Abstract: Chemoenzymatic Synthesis of trans-4,5-Dihydroxycyclopent-2-enones: Conversion to D-1-Deoxynojirimycin

Autor: Adam Golebiowski, Carl R. Johnson, John L. Esker, Bipin M. Nerurkar, Hari Sundram
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 26
ISSN: 0931-7597
DOI: 10.1002/chin.199541119
Popis: (4R,5S)-trans-4,5-Bis(tert-butyldimethylsilyloxy)cyclopent-2-enone 8 and (4R,5S)-trans-4,5-di(benzyloxy)cyclopent-2-enone 20 are prepared by equilibration of the corresponding cis derivatives; enone 8 is transformed into the glucosidase inhibitor, D-1-deoxynojirimycin 14.
Databáze: OpenAIRE