Nerve Growth Factor: Optic and Ultrastructural Findings on Facial Nerve Degeneration in the Rabbit

Autor: José Luis Llorente, M. Alvarez-Uria, M. J. Bernardo, Carlos Suárez, Pilar Ablanedo
Rok vydání: 1994
Předmět:
Zdroj: The Facial Nerve ISBN: 9783540576860
DOI: 10.1007/978-3-642-85090-5_164
Popis: After the discovery by Hamburger [3] and Levi-Montalcini [5] of the nerve growth factor (NGF), other neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and cilliary neurotrophic factor (CNTR) [6] were found. At present we do not know whether a specific trophic factor exists that acts on motor fibers. On the other hand, the effect of the NGF on sensory fibers is known. Therefore, we used this factor locally on the transected area of a mixed nerve, such as the facial nerve, evaluating its possible action during the degeneration period.
Databáze: OpenAIRE