A novel long non-coding RNA LSAMP-1 is down-regulated in non-small cell lung cancer and predicts a poor prognosis

Autor: wei gong, Fuman Qiu, Yinyan Li, Lei Yang, Yuanyuan Wang, Jianfeng Xian, Xin Zhang, Yifeng Zhou, Xinhua Wang, Guibin Qiao, Cuiyi Chen, Xincheng Gao, Jiachun Lu
Rok vydání: 2020
DOI: 10.21203/rs.2.21107/v1
Popis: Background There is very little known about how long non-coding RNAs (lncRNAs) are associated with membrane proteins in lung cancer. The limbic system-associated membrane protein ( LSAMP ) has been reported to play a tumor suppressor role in a variety of cancers.Methods We aimed to explore the lncRNA associated with LSAMP and explore its effects on lung cancer.Results We found that Lnc-LSAMP-1 was significantly down-regulated in 170 cases of lung tumor tissues when compared to the adjacent non-cancerous tissues (p
Databáze: OpenAIRE