Discontinuing voriconazole induced no completely regression of multiple cutaneous squamous cell carcinoma in a hematopoietic stem cell transplant patient
| Autor: | Mutsumi Okada, Aika Okuno, Fukumi Furukawa, Yuki Yamamoto, Naoyuki Anzai, Atsuko Tanabe, Yuka Hirakawa |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Voriconazole
medicine.medical_specialty Cutaneous squamous cell carcinoma Erythema business.industry medicine.medical_treatment Immunology Actinic keratosis Hematopoietic stem cell Hematopoietic stem cell transplantation medicine.disease Dermatology medicine.anatomical_structure Oncology medicine Immunology and Allergy Pharmacology (medical) Transplant patient medicine.symptom Phototoxicity business medicine.drug |
| Zdroj: | Trends in Immunotherapy. 2 |
| ISSN: | 2573-5985 |
| DOI: | 10.24294/ti.v2.i4.1079 |
| Popis: | Voriconazole is a universal anti-fungal prophylaxis, which is frequently taken to the patients after hematopoietic stem cell transplantation and solid organ transplantation. Voriconazole can cause phototoxicity, multiple erythema in sun-exposed areas may develop actinic keratosis and cutaneous squamous cell carcinoma (cSCC) while taking voriconazole. In North America and Europe, case reports of phototoxicity and aggressive cSCC in patients on voriconazole have been documented. Also 4 cases of voriconazole-associated cSCC have recently been reported in Japan. We describe a Japanese woman with multiple cSCC associated with recurrence of cSCC after discontinuing voriconazole. |
| Databáze: | OpenAIRE |
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