Syntheses and Insecticidal Activity of Spirocyclic Tetronic Acid Derivatives Containing Oxime Ether Moiety

Autor:	Jin-Hao Zhao, Yang Zhao, Zhengang Xie, Jing-Li Cheng, Shao-Wei Fang
Rok vydání:	2020
Předmět:	Stereochemistry Chemistry 02 engineering and technology General Chemistry Carbon-13 NMR 010402 general chemistry 021001 nanoscience & nanotechnology Oxime ether 01 natural sciences 0104 chemical sciences Proton NMR Moiety Bioassay Spirotetramat 0210 nano-technology Tetronic acid
Zdroj:	Chemical Research in Chinese Universities. 36:810-815
ISSN:	2210-3171 1005-9040
DOI:	10.1007/s40242-020-0003-8
Popis:	In order to develop novel spirocyclic tetronic acid lead compounds, a series of new spirocyclic tetronic acid derivatives containing oxime ether moiety was synthesized and bioassayed. The structures of 16 target com-pounds were characterized by 1H NMR spectra, 13C NMR spectra and high-resolution mass spectrometer(HRMS). Preliminary bioassays indicated that most of the title compounds displayed excellent insecticidal activity against Aphis fabae and Nilaparvata lugens at 100 mg/L. In particular, compound 6k showed the similar activity(LC50= 6.87 mg/L) against A. fabae as the spirotetramat(LC50=4.56 mg/L) and had better effects(LC50=1.64 mg/L) against N. lugens in comparison with spirotetramat(LC50=7.90 mg/L). The study showed that compound 6k exhibited more promising and broad-spectrum insecticide activity and may serve as a new insecticidal agent for sucking pests.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5cea22479a4a6c87ef1d17e4cda684c7 https://doi.org/10.1007/s40242-020-0003-8 Zobrazit plný text záznamu Full text from SpringerLink