Pre-clinical Testing of the Polymer Implants Enriched of Ceramic Materials with aim on Rate of Osteointegration in a Rabbit Model

Autor:	Marcel Modrák, Radovan Hudák, Marianna Trebuňová, Lukáš Mitrík, Jana Klímová, Ladislav Molnár, Marek Schnitzer, Jozef Živčák
Rok vydání:	2020
Předmět:	chemistry.chemical_classification Biocompatible polymers Materials science Animal subject Soft tissue General Medicine Polymer Osseointegration chemistry visual_art Rabbit model visual_art.visual_art_medium Femoral bone Ceramic Biomedical engineering
Zdroj:	Acta Mechanica Slovaca. 24:14-18
ISSN:	1339-3073 1335-2393
DOI:	10.21496/ams.2020.013
Popis:	The purpose of this paper was writing down the process of preclinical testing which consisted from usage of bioinert polymer material enriched with bioactive ceramic elements. The testing was preceded by a study of the current state and methods of implantation of polymer implants. The created samples were implanted into the animal subject femoral bone with purpose to observe the rate of osteointegration process for twelve weeks. Subsequently were the bones dissected, stripped of soft tissue and observed under stereomicroscope and submitted to histological evaluation. The whole process was detailly recorded and it is prepared for further clinical studies in field of implantation of biocompatible polymer materia
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5cad145cd9f2039772e894fafea27e4a https://doi.org/10.21496/ams.2020.013 Zobrazit plný text záznamu