Laser speckle imaging and wavelet analysis of cerebral blood flow associated with the opening of the blood–brain barrier by sound

Autor:	Madina Sagatova, Anastasiya Bodrova, Valery V. Tuchin, N. Shushunova, Artem Gekalyuk, Alexander Shirokov, Oksana V. Semyachkina-Glushkovskaya, Ilana Agranovich, Chi Zhang, Ali Esmat Shareef, V. Fedorova, Elena Saranceva, Daqing Zhu, Alexander Khorovodov, Arkady S. Abdurashitov, Nikita A. Navolokin, Olga N. Pavlova, M. Ulanova, Alexey N. Pavlov
Rok vydání:	2017
Předmět:	Cerebral veins medicine.medical_specialty 02 engineering and technology Blood–brain barrier Contrast imaging 01 natural sciences 010309 optics Speckle pattern Wavelet Optics Internal medicine 0103 physical sciences medicine Electrical and Electronic Engineering Microvessel business.industry Laser Speckle Imaging 021001 nanoscience & nanotechnology Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials medicine.anatomical_structure nervous system Cerebral blood flow cardiovascular system Cardiology 0210 nano-technology business
Zdroj:	Chinese Optics Letters. 15:090002
ISSN:	1671-7694
DOI:	10.3788/col201715.090002
Popis:	The cerebral blood flow (CBF) alterations related to sound-induced opening of the blood–brain barrier (BBB) in adult mice are studied using laser speckle contrast imaging (LSCI) and wavelet analysis of vascular physiology. The results clearly show that the opening of the BBB is accompanied by the changes of venous but not microvessel circulation in the brain. The elevation of the BBB permeability is associated with the decrease of venous CBF and the increase of its complexity. These data suggest that the cerebral veins rather than microvessels are sensitive components of the CBF related to the opening BBB.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5ca86529c88158d3e60751aadf3c0be7 https://doi.org/10.3788/col201715.090002 Zobrazit plný text záznamu