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The effects of dosage of follicle stimulating hormone (FSH), vehicle and time of injection on ovulation rate and prolificacy were evaluated during the anestrous season. Ewes on four farms ( n =445) were treated with a CIDR-G ® device for 5 days and exposed to rams upon removal of the insert (CRRI, day 0). A 3×2×2 factorial arrangement tested effects of dosage of FSH (Folltropin ® ; 0, 42 or 68 mg NIH-FSH-P1), vehicle (saline:propylene glycol 1:4, v/v [PGL], or 50% polyvinylpyrrolidone K 29–32 [PVP]) and time of injection (12 or 36 h before CRRI). Follicular growth was monitored by ultrasonography in four ewes per treatment at injection of FSH, at CRRI, and on days 1–3 post-CRRI. All ewes were examined by ultrasonography on days 10–14 for ovulation rate, and on days 26–31 and 46–51 for pregnancy and number of embryos. The largest follicle (F 1 ) increased in diameter (mm) between FSH injection (5.3±0.1) and day 1 (6.1±0.1; P 1 was larger at CRRI ( P ≤0.05) in ewes receiving 42 than 0 mg FSH, and 68 than 42 mg FSH. The F 2 increased in diameter ( P P P P P P P P |
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