Incidence and clinical significance of bacterial and fungal contamination of the preservation solution in liver transplantation
| Autor: | T. Piardi, E. Ghislotti, H. Flicoteaux, P. Wolf, M. Cag, F. Panaro, M. Audet, J. Cinqualbre, T.M. Jarzembowski, F. Gheza |
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| Rok vydání: | 2011 |
| Předmět: |
Transplantation
Pathology medicine.medical_specialty Drug Contamination biology business.industry Incidence (epidemiology) medicine.medical_treatment Microorganism Liver transplantation Contamination biology.organism_classification Microbiology Infectious Diseases Medicine Clinical significance business Perfusion Bacteria |
| Zdroj: | Transplant Infectious Disease. 13:84-88 |
| ISSN: | 1398-2273 |
| Popis: | A perfusion fluid used in the preservation of the grafted liver represents a medium suitable for microorganism growth. In this observational study, a sample of 232 transplanted livers was collected. Perfusion fluid samples were stored for microbiological analysis from harvested donors. Bacteria were isolated in 91 out of 232 samples, post-operative infections related to contaminated perfusion solution occurred in 13 cases. The contamination rate of the preservation medium appears to be high, but postoperative infections occurs rarely. We suggest periodic detection and a protocol in place designed for antibiotic use for transplanted patients exposed to contaminated perfusion solution. |
| Databáze: | OpenAIRE |
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