Budd–Chiari syndrome versus Pyrrolizidine alkaloids-induced hepatic sinusoidal obstructive syndrome: A multi-center study

Autor: Yaru Tong, Yuzheng Zhuge, Ming Zhang, Zexue Qi, Wei Wu, Jinjun Chen, Fuliang He, Xiaofeng Zhang, Feng Zhang, Taishun Li, Bin Zhang, Wei Zhang, Qin Yin, Pengxu Ding, Guangchuan Wang
Rok vydání: 2022
DOI: 10.21203/rs.3.rs-1730035/v1
Popis: Background Budd-Chiari syndrome (BCS), especially BCS-hepatic vein occlusion type (BCS-HV), and Pyrrolizidine alkaloids-induced hepatic sinusoidal obstructive syndrome (PA-HSOS) share many clinical characteristics. In this study, we comprehensively compare the two diseases to identify key characteristics. Methods 139 patients with BCS-HV and 257 PA-HSOS patients admitted to six hospitals between January 2014 and October 2021 were retrospectively analyzed. The two groups were then comprehensively compared and analyzed clinically. Results Among the 139 BCS-HV and 257 PA-HSOS patients, the mean age and the median time from symptom onset to the first visit have a statistical difference. 257 PA-HSOS patients all had a history of taking PA-containing plants, while no patients in the BCS-HV group were exposed to PA-containing plants (p
Databáze: OpenAIRE