B-Cell Prolymphocytic Leukemia With t(8;14) Translocation

Autor: Helen J. Lawce, Elaine S. Jaffe, Susan B. Olson, Ellen Flatley, Guang Fan
Rok vydání: 2012
Předmět:
Zdroj: American Journal of Clinical Pathology. 138:A095-A095
ISSN: 1943-7722
0002-9173
DOI: 10.1093/ajcp/138.suppl2.146
Popis: B-cell prolymphocytic leukemia remains a controversial entity, and its molecular pathogenesis is unknown. We identified a 62-year-old woman who presented with weight loss and abdominal pain. She was found to have massive splenomegaly (26 cm) and lymphocytosis (30.5 K/cu mm). The lymphocytes were mature with a moderate amount of basophilic cytoplasm and prominent nucleoli, which are typical features of prolymphocytes. …
Databáze: OpenAIRE