Correlation of symptoms, quality of life, and functional status in head and neck cancer patients receiving radiation therapy ± chemotherapy
| Autor: | Marylin Dodd, J. Lee, K. A. Bank, J. Quivey, Maria Cho |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Cancer Research
medicine.medical_specialty Chemotherapy education.field_of_study Side effect business.industry medicine.medical_treatment Head and neck cancer Population medicine.disease Surgery Clinical trial Radiation therapy Oncology Quality of life Internal medicine medicine Mucositis business education |
| Zdroj: | Journal of Clinical Oncology. 26:20671-20671 |
| ISSN: | 1527-7755 0732-183X |
| DOI: | 10.1200/jco.2008.26.15_suppl.20671 |
| Popis: | 20671 Background: Oral mucositis is a major side effect of radiation therapy (RT) to the head and neck. Few studies have reported the correlations of prevalent symptoms, quality of life (QOL), and functional status in this population. The purpose of this study is to increase our understanding of these issues. Methods: In this clinical trial testing an innovative mouthwash, symptoms (Symptom Checklists), functional status (Karnofsky Functional Status [KPS]), quality of life (QOL-CA), and the Oral Mucositis Assessment Scale (OMAS) subjective pain score were measured at four times (beginning of RT [T1], onset of mucositis [T2], end of RT [T3], and healing of mucositis [T4]) over an approximate 10-12 week period. Results: Forty-three head and neck cancer patients were enrolled at T1: 78% male, 62% white, 67% married; 15.3 mean education years; 44% employed full time; 58% squamous cell carcinoma; 98% received IMRT, 6463.9 cGY mean total radiation dose, 56% received concurrent CTX. Mean days to onset of mucosit... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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