Efficacy of agglutination test in diagnosis of motile Aeromonas septicemia in Nile tilapia (Oreochromis niloticus)
| Autor: | G Mitterschiffthaler, F J Richardson, S Scharz, K. S. Khuenl-Brady |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
business.industry
Maintenance dose Neuromuscular Effects medicine.medical_treatment Multiple dose 03 medical and health sciences Dose–response relationship 0302 clinical medicine Muscle relaxation Statistical significance Anesthesia Atracurium besilate Medicine Intubation 030212 general & internal medicine business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Egyptian Journal for Aquaculture. 8:1-12 |
| ISSN: | 2636-3984 |
| DOI: | 10.21608/eja.2018.44524 |
| Popis: | The time-course of the neuromuscular effects of vecuronium (n = 25) and atracurium (n = 25) has been compared at three different levels of maintenance dose in anaesthetized patients. Following intubation with vecuronium 0.1 mg kg-1 or atracurium 0.5 mg kg-1, surgical muscle relaxation was maintained by using increments of equipotent maintenance doses equivalent to 0.5, 1.0 and 1.5 x ED95 for each drug. Repeat doses were administered each time the twitch height, depressed by the previous dose, returned to 25% of its control value. The apparent increase in the duration of action, i.e. the difference between the duration of the last and the first maintenance dose, did not reach statistical significance and approximated 3 +/- 2, 6 +/- 4, 11 +/- 5 and 3 +/- 2, 8 +/- 13, 5 +/- 7 min following the low, medium and high maintenance doses of vecuronium and atracurium, respectively. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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