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Introduction: One of the most common nosocomial infections is urinary tract infection (UTI), which more commonly seen in patients with urethral catheter. Inappropriate use of urinary catheter can lead to certain complications including infection. Objectives: The aim of this study was to evaluate the effect of using mupirocin and betadineimpregnated urethral catheters in comparison with conventional catheterization on the incidence rate of catheter-related bacteriuria (CRB) and UTIs. Patients and Methods: In this parallel randomized clinical trial, phase III, a total of 150 patients (male and female) ranging from 18-75 years who needed urinary catheterization were randomly assigned into three evenly distributed groups; betadine, mupirocin, and conventional (control) through permuted block randomization. Sterile urine samples were examined for bacteriuria after catheter insertion and at the time of catheter removal. Results: The mean age of the patients was 49.81 (±15.11) years. UTI was seen most frequently in the conventional group (56%), and least frequently in the mupirocin group (24%) (P |
