Role of leukocyte breakdown products in increasing the resistance of macrophages to ornithosis virus

Autor:	A. S. Tolybekov, V. E. Pigarevskii, V. N. Kokryakov, I. P. Ashmarin
Rok vydání:	1976
Předmět:	Histone Granuloma formation biology Cytoplasm biology.protein Ornithosis General Medicine Ornithosis virus Virology General Biochemistry Genetics and Molecular Biology Virus In vitro Microbiology
Zdroj:	Bulletin of Experimental Biology and Medicine. 81:729-732
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00797146
Popis:	The dynamics of formation of macrophagal granulomas in the liver after intravenous infection of albino mice with ornithosis virus was studied. During granuloma formation the macrophages pass through a stage of reutilization of breakdown products of leukocytes and they become resistant to ornithosis virus. Together with remnants of leukocytes, histones and cationic proteins with high antiornithosis activity in vitro may also enter the cytoplasm of the macrophages. The increased resistance of macrophages to the virus after reutilization of the leukocyte breakdown products is evidently one of the mechanisms of resistance formation in inflammatory foci associated with ornithosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5c16801042aa321d416ab9f1d3fa2c26 https://doi.org/10.1007/bf00797146 Zobrazit plný text záznamu Full text from SpringerLink