ChemInform Abstract: Formation of N-Alkylpyrroles via Intermolecular Redox Amination

Autor:	Jon A. Tunge, Miranda A. Paley, Shelli R. Waetzig, Ranjan Jana, Nirmal K. Pahadi
Rok vydání:	2010
Předmět:	chemistry.chemical_classification chemistry Reducing agent General Medicine Brønsted–Lowry acid–base theory Redox Combinatorial chemistry Reductive amination Alkyl Amination Stoichiometry Catalysis
Zdroj:	ChemInform. 41
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.201014101
Popis:	A wide variety of aldehydes, ketones, and lactols undergo redox amination when allowed to react with 3-pyrroline in the presence of a mild Bronsted acid catalyst. This reaction utilizes the inherent reducing power of 3-pyrroline to perform the equivalent of a reductive amination to form alkyl pyrroles. In doing so, the reaction avoids stoichiometric reducing agents that are typically associated with reductive aminations. Moreover, the redox amination protocol allows access to alkyl pyrroles that cannot be made via standard reductive amination.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5c02d6eb5fbdb7f690be1a839184343f https://doi.org/10.1002/chin.201014101 Zobrazit plný text záznamu Plný text