Action of specific placental proteins ? Trophoblastic ?-glycoprotein and chorionic ?1-microglobulin ? On proliferation of lymphocytes and malignant fibroblastsin vitro

Autor: Yu. K. Gorlina, I. N. Golovistikov, D. D. Petrunin, T. M. Tsagaraeva, Yu. S. Tatarinov
Rok vydání: 1981
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 91:362-365
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00839376
Popis: Variations in the membrane potential and in DNA, RNA and protein synthesis were studied in experiments on rats at varying times after hepatectomy. Hyperpolarization of the hepatocyte plasmatic membrane was shown to develop during liver regeneration along with activation of DNA, RNA and protein synthesis. Actinomycin D prevented the development of hyperpolarization and activation of RNA and protein synthesis. Administration of liver filtrates from hepatectomized rats to intact recipients induced hyperpolarization of liver cells. Activation of protein biosynthesis following hepatectomy resulted in hyperpolarization of the cell membrane, this action being mediated via formation of a specific membrane-active factor.
Databáze: OpenAIRE