An Improved Procedure for Preparation of Carbapenem Antibiotic: Meropenem

Autor:	Hashim Nizar, Bishwa Prakash Rai, Shailendra Kumar Singh, Neera Tewari, Vinod George, Mohan Prasad
Rok vydání:	2007
Předmět:	Carbapenem medicine.drug_class Chemistry Organic Chemistry Antibiotics biochemical phenomena metabolism and nutrition bacterial infections and mycoses Combinatorial chemistry Meropenem polycyclic compounds medicine bacteria Physical and Theoretical Chemistry Reverse osmosis medicine.drug
Zdroj:	Organic Process Research & Development. 11:773-775
ISSN:	1520-586X 1083-6160
DOI:	10.1021/op700088y
Popis:	An efficient synthesis of a 1β-methyl carbapenem antibiotic, meropenem, is described. The present process does not involve cryogenic temperatures, chromatographic purification, or reverse osmosis and is amenable to large scale synthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5bf422829328dc1adf44511294b3ec32 https://doi.org/10.1021/op700088y Zobrazit plný text záznamu