Validation analytique en immunohématologie érythrocytaire

Autor: M. Delamaire, F. Roubinet, Jacques Chiaroni, A. Lejealle, L. Mannessier
Rok vydání: 2000
Předmět:
Zdroj: Transfusion Clinique et Biologique. 7:51s-54s
ISSN: 1246-7820
DOI: 10.1016/s1246-7820(00)80017-8
Popis: Summary In a transfusional or fœto-maternal context, hemolysis by incompatibility due to anti-erythrocyte antibodies (regular or irregular) remains the most frequent and most serious immunological risk in the receiver. In order to prevent this risk, a number of actions must be taken, such as the realization of the immunohematologic analyses for which the methodological practices have been legislated because of their serious clinical consequences. Several elements play a role in the reliability of the analyses and their results: the selection of the reagents and their validation in the routine technique used; the validation of reception; the controls involved in secondary preparations (e.g., blood cells reagent); and the daily internal controls. All this requires the choice of adapted controls and the management of possible anomalies.
Databáze: OpenAIRE