Chiral 1,4-diazepinones and 1,4-thiazepinones by diastereoselective ring chain transformation of α,β unsaturated lactones or lactams

Autor:	Jürgen Liebscher, Jörg Bohrisch, Heike Faltz, Michael Pätzel
Rok vydání:	1994
Předmět:	Transformation (genetics) chemistry.chemical_compound Chain (algebraic topology) Chemistry Stereochemistry Organic Chemistry Drug Discovery Cysteamine Ring (chemistry) Biochemistry
Zdroj:	Tetrahedron. 50:10701-10708
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(01)89262-0
Popis:	Butenolides or α,β-unsaturated lactams 1 react with 1,2-diamines cysteamine or 2-aminothiophenol by addition and ring transformation giving new chiral, hydrogenated or partly hydrogenated 7-(α-hydroxyalkyl) and 7-(α-aminoalkyl)-1,4-diazepin-5-ones and 1,4-thiazepin-5-ones 4.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5bd8256b72df49b3088aba944d733158 https://doi.org/10.1016/s0040-4020(01)89262-0 Zobrazit plný text záznamu