Comparative Effects of Dexamethasone and Methylprednisolone on Peritumoral Brain Edema

Autor:	D. Zerbi, G. Schmitt, M. Zuccarello, G. Macchia, G. C. Andrioli
Rok vydání:	1991
Předmět:	medicine.medical_specialty medicine.diagnostic_test business.industry Brain edema Urology Computed tomography Metastatic brain tumor Bolus (medicine) Methylprednisolone Prospective trial medicine business Peritumoral Brain Edema Dexamethasone medicine.drug
Zdroj:	Neuro-Oncology ISBN: 9789401053907
DOI:	10.1007/978-94-011-3152-0_45
Popis:	We evaluated the efficacy of methylprednisolone (MP) and dexamethasone (DM) in a randomized, prospective trial in 15 patients with primary and/or metastatic brain tumors. MP was given to 7 patients as an IV bolus of 1 gm, and tapered off in the following 7 days. DM was given to 8 patients at the daily dosage of 16 mgs for 7 days, and the day of surgery, and tapered off in the following 7 days. After 7 and 14 days, only the patients treated with MP showed a significant reduction in peritumoral brain edema volume measured by CT scan (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5bcb989039c28b4dbc2c4bdc2379c25f https://doi.org/10.1007/978-94-011-3152-0_45 Zobrazit plný text záznamu