Monitored Anesthesia Care Versus Intubated General Anesthesia for Open Heart Surgery Under Cardiopulmonary Bypass: A Prospective Cohort Study

Autor: Wei Tang, Yue Yong, Wen-ting Chen, Guo-qiang Fu, Lan Yuan, Lan Wang, Jian Wang, Yong-Qiang Wang, Jian-gang Song, Xing Li
Rok vydání: 2020
Předmět:
Zdroj: SSRN Electronic Journal.
ISSN: 1556-5068
DOI: 10.2139/ssrn.3688223
Popis: Background: Though Cardiac surgery under cardiopulmonary bypass (CPB) under epidural anesthesia in conscious patients is associated with increased risk of epidural hematoma. We developed a monitored anesthesia care (MAC) platform for cardiac surgery under CPB. In the current prospective study, we investigated the safety and effectiveness of the MAC platform versus intubated general anesthesia (IGA) in patients receiving elective open-heart surgery. Methods: The study included adult patients who were scheduled to undergo open-heart surgery under CPB at our hospital between April 2012 and February 2017. MAC consisted of local anesthesia at the site of sternotomy, sedation with dexmedetomidine, analgesia with remifentanil/sufentanil, and electroacupuncture. MAC versus IGA was chosen by the patients. Findings: Eleven patients received MAC and 13 patients received IGA. The two groups were comparable in the demographic, baseline and operative variables. No conversion occurred from MAC to IGA. No major complications occurred during the surgery in both groups. No confirmed awareness events after surgery were reported in both groups. There was no statistical difference in the incidence of postoperative complications between the two groups (P >0.05). The intraoperative consumption of sufentanil and remifentanil was significantly lower in the MAC group than the IGA group (P < 0.001). The time to drinking was significantly shorter in the MAC group (2.14±0.90 h) than the IGA group (22.31±3.33 h) (P
Databáze: OpenAIRE