Synthesis and reactions of 4-trifluoromethyl-3-cyano pyridine-2(1H)-thione/one derivatives

Autor:	Nora M. Rateb
Rok vydání:	2011
Předmět:	chemistry.chemical_compound Cyanoacetamide Trifluoromethyl chemistry Reagent Pyrazolopyridine Pyridine Organic chemistry General Chemistry Grinding
Zdroj:	Journal of Sulfur Chemistry. 32:611-622
ISSN:	1741-6000 1741-5993
DOI:	10.1080/17415993.2011.628994
Popis:	4,4,4-Trifluoro-1-(thiophen-2-yl)butane-1,3-dione was reacted by grinding with cyanothioacetamide and cyanoacetamide under solvent-free conditions at 25 °C to give pyridine-2(1H)thione/one derivatives in excellent yields. These compounds were further reacted by grinding with different halogenated reagents to give 2-S/O-alkyl pyridine derivatives. The latter compounds were utilized for the synthesis of thieno[2,3-b]pyridine, pyrazolopyridine, pyridothienopyrimidine and pyridothienooxazinone derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5bc20ffcb61d53975ab18fe7a993e52c https://doi.org/10.1080/17415993.2011.628994 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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