Phase I study of amonafide + cytosine arabinoside (AraC) in patients with poor risk acute myeloid leukemia (AML)

Autor: R. Dubon, M. Drouin, C. K. Grieshaber, Jonathan E. Kolitz, M. A. Boss, M. Champagne, Steven L. Allen, Daniel R. Budman, Ante Sven Lundberg, S. Devost
Rok vydání: 2005
Předmět:
Zdroj: Journal of Clinical Oncology. 23:6602-6602
ISSN: 1527-7755
0732-183X
DOI: 10.1200/jco.2005.23.16_suppl.6602
Popis: 6602 Background: Amonafide (Am) is an ATP independent topoisomerase 2 inhibitor that in prior clinical studies demonstrated activity in breast cancer (18–25% response rate (RR)) and prostate cancer...
Databáze: OpenAIRE