Simulated Gastric Acid Promotes the Horizontal Transfer of Multidrug Resistance Genes across Bacteria in the Gastrointestinal Tract at Elevated pH Levels

Autor: Hai-yan Wu, Zi-lin Wei, Dan-yang Shi, Hai-bei Li, Xin-mei Li, Dong Yang, Shu-qing Zhou, Xue-xia Peng, Zhong-wei Yang, Jing Yin, Tian-jiao Chen, Jun-wen Li, Min Jin
Rok vydání: 2023
Předmět:
Zdroj: Microbiology Spectrum.
ISSN: 2165-0497
DOI: 10.1128/spectrum.04820-22
Popis: The low pH of gastric acid kills unwanted microorganisms, in turn affecting their inhabitation in the intestine. Hence, studies on the factors that influence antibiotic resistance gene (ARG) propagation in the gastrointestinal tract and on the underlying mechanisms are limited.
Databáze: OpenAIRE